Urinary copper levels are associated with bronchiectasis in non-smokers living near a petrochemical complex.

ABSTRACT: The incidence of respiratory diseases has been associated with copper in particulate matter; however, the relationship between urinary copper levels and interstitial lung changes remains unclear. Therefore, we conducted a population-based study in southern Taiwan between 2016 and 2018, excluding individuals with a history of lung carcinoma, pneumonia, and cigarette smoking. Low-dose computed tomography (LDCT) was performed to detect lung interstitial changes, including the presence of ground-glass opacity or bronchiectasis in LDCT images. We categorized urinary copper levels into quartiles (Q1: ≤10.3; Q2: >10.4 and ≤14.2; Q3: >14.3 and ≤18.9; and Q4: >19.0 μg/L) and analyzed the risk of interstitial lung changes using multiple logistic regression analysis. The urinary copper levels were si

SUBMITTER: Wang CW 

PROVIDER: S-EPMC10202350 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature