Hierarchical Spinning of Janus Textiles with Anisotropic Wettability for Wound Healing.

ABSTRACT: Wound healing and tissue repair are recognized as basic human health problems worldwide. Attempts to accelerate the reparative process are focused on developing functional wound dressings. Herein, we present novel Janus textiles with anisotropic wettability from hierarchical microfluidic spinning for wound healing. The hydrophilic hydrogel microfibers from microfluidics are woven into textiles for freeze-drying treatment, followed by the deposition of electrostatic spinning nanofibers composed of hydrophobic polylactic acid (PLA) and silver nanoparticles. The electrospun nanofiber layer can be well coupled with the hydrogel microfiber layer to generate Janus textiles with anisotropic wettability due to the roughness of the hydrogel textile surface and the incomplete evaporation of PLA solu

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10202375 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature