Genomic and Phylogenetic Analysis of a Multidrug-Resistant bla_NDM-carrying Klebsiella michiganensis in China.

ABSTRACT:

Objective

Klebsiella michiganensis is an emerging hospital-acquired bacterial pathogen. However, there is a dearth of knowledge on the antimicrobial resistance and transmission of K. michiganensis. Here, we characterized the microbiological and genomic features of a carbapenem-resistant K. michiganensis strain harboring the bla_NDM-1 gene in China.

Methods

K. michiganensis strain 2563 was recovered from the sputum sample of a hospitalized patient with pulmonary infection. Whole-genome sequencing of K. michiganensis strain 2563 was conducted using both the short-read Illumina and long-read MinION platforms to thoroughly characterize the genetic context of bla_NDM-carrying plasmid in K. michiganensis 2

SUBMITTER: Jiang T 

PROVIDER: S-EPMC10202706 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature