Growth hormone effect on body composition of children born small for gestational age: a systematic review.

ABSTRACT:

Objective

The present study aimed to evaluate the effects of GH treatment on the body composition of children born with SGA.

Methods

This study is a systematic review of the literature. CINAHL, Embase; Medline/Pubmed, Scopus and Web of Science were searched from inception to March 2022.

Results

Four studies met the inclusion criteria, with an intervention time of 1 to 3 years, using doses from 0.03 to 0.07 mg/kg/day of GH. Bone densitometry by dual-energy X-ray absorptiometry (DXA) with whole-body scans was the most used method to assess body composition. Most studies (n = 3) had SGA children as a control group with the same characteristics as the case group; the mean age was similar between the groups (minimum of 5.1 ± 1.4 years and maximum of 6.7 ± 1 0.8 years) and

SUBMITTER: Kuhl AM 

PROVIDER: S-EPMC10202731 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature