CT based intratumor and peritumoral radiomics for differentiating complete from incomplete capsular characteristics of parotid pleomorphic adenoma: a two-center study.

ABSTRACT:

Objective

Capsular characteristics of pleomorphic adenoma (PA) has various forms. Patients without complete capsule has a higher risk of recurrence than patients with complete capsule. We aimed to develop and validate CT-based intratumoral and peritumoral radiomics models to make a differential diagnosis between parotid PA with and without complete capsule.

Methods

Data of 260 patients (166 patients with PA from institution 1 (training set) and 94 patients (test set) from institution 2) were retrospectively analyzed. Three Volume of interest (VOIs) were defined in the CT images of each patient: tumor volume of interest (VOI_tumor), VOI_peritumor, and VOI_{intra-plus peritumor}. Radiomics features were extracted from each VOI and used to train nine

SUBMITTER: Li S 

PROVIDER: S-EPMC10203084 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature