Vitamin B₁₂ is not shared by all marine prototrophic bacteria with their environment.

ABSTRACT: Vitamin B₁₂ (cobalamin, herein B₁₂) is an essential cofactor involved in amino acid synthesis and carbon resupply to the TCA cycle for most prokaryotes, eukaryotic microorganisms, and animals. Despite being required by most, B₁₂ is produced by only a minor fraction of prokaryotes and therefore leads to complex interaction between prototrophs and auxotrophs. However, it is unknown how B₁₂ is provided by prototrophs to auxotrophs. In this study, 33 B₁₂ prototrophic alphaproteobacterial strains were grown in co-culture with Thalassiosira pseudonana, a B₁₂ auxotrophic diatom, to determine the bacterial ability to support the growth of the diatom by sharing B₁₂. Among these strains, 18 were identified to share B₁₂

SUBMITTER: Sultana S 

PROVIDER: S-EPMC10203341 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature