A systematic review and physiology of pulmonary artery pulsatility index in left ventricular assist device therapy.

ABSTRACT:

Objectives

Right heart failure (RHF) is a major complication following left ventricular assist device (LVAD) implantation. Pulmonary artery pulsatility index (PAPi) has been evaluated as a haemodynamic marker for RHF, but PAPi is dependent on pulmonary vascular resistance (PVR). We conducted a systematic review to assess the relationship between PAPi and RHF and death in patients undergoing LVAD implantation and examined the relationship between PAPi cut-off and PVR.

Methods

We searched PubMed, EMBASE, CENTRAL and manually screened retrieved references to identify all clinical studies reporting PAPi in adult patients with a durable LVAD. Eligibility criteria were prespecified and 2 reviewers independently screened and extracted data; the Newcastle-Ottawa Scale was used to as

SUBMITTER: Yim IHW 

PROVIDER: S-EPMC10203377 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature