Prolonged mechanical ventilation after lung transplantation: risks factors and consequences on recipient outcome.

ABSTRACT:

Background

Risk factors and the incidence of prolonged mechanical ventilation (PMV) after lung transplantation (LT) have been poorly described. The study assessed predictive factors of PMV after LT.

Methods

This observational, retrospective, monocentric study included all patients who received LT in Bichat Claude Bernard Hospital between January 2016 and December 2020. PMV was defined as a duration of MV > 14 days. Independent risk factors for PMV were studied using multivariate analysis. One-year survival depending on PMV was studied using Kaplan Meier and log-rank tests. A p value <0.05 was defined as significant.

Results

224 LT recipients were analysed. 64 (28%) of them received PMV for a median duration of 34 [26-52] days versus 2 [1-3] days without PMV. In

SUBMITTER: Atchade E 

PROVIDER: S-EPMC10203407 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature