Integrative roles of human amygdala subdivisions: Insight from direct intracerebral stimulations via stereotactic EEG.

ABSTRACT: Substantial studies of human amygdala function have revealed its importance in processing emotional experience, autonomic regulation, and sensory information; however, the neural substrates and circuitry subserving functions have not been directly mapped at the level of the subnuclei in humans. We provide a useful overview of amygdala functional characterization by using direct electrical stimulation to various amygdala regions in 48 patients with drug-resistant epilepsy undergoing stereoelectroencephalography recordings. This stimulation extends beyond the anticipated emotional, neurovegetative, olfactory, and somatosensory responses to include visual, auditory, and vestibular sensations, which may be explained by the functional connectivity with cortical and subcortical regions due to ev

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10203795 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature