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S100 proteins in cardiovascular diseases.


ABSTRACT: Cardiovascular diseases have become a serious threat to human health and life worldwide and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular diseases have become a focus for public health experts. The expression of S100 proteins is cell- and tissue-specific; they are implicated in cardiovascular, neurodegenerative, and inflammatory diseases and cancer. This review article discusses the progress in the research on the role of S100 protein family members in cardiovascular diseases. Understanding the mechanisms by which these proteins exert their biological function may provide novel concepts for preventing, treating, and predicting cardiovascular diseases.

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC10204201 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

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S100 proteins in cardiovascular diseases.

Zhou Yue Y   Zha Yiwen Y   Yang Yongqi Y   Ma Tan T   Li Hongliang H   Liang Jingyan J  

Molecular medicine (Cambridge, Mass.) 20230522 1


Cardiovascular diseases have become a serious threat to human health and life worldwide and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular diseases have become a focus for public health experts. The expression of S100 proteins is cell- and tissue-specific; they are implicated in cardiovascular, neurodegenerative, and inflammatory diseases and cancer. This review article discusses the progress in the research on the role of S100 protein family members in  ...[more]

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