The Ras small GTPase RSR1 regulates cellulase production in Trichoderma reesei.

ABSTRACT:

Background

Lignocellulose is the most abundant renewable resource in the world and has attracted widespread attention. It can be hydrolyzed into sugars with the help of cellulases and hemicellulases that are secreted by filamentous fungi. Several studies have revealed that the Ras small GTPase superfamily regulates important cellular physiological processes, including synthesis of metabolites, sporulation, and cell growth and differentiation. However, it remains unknown how and to what extent Ras small GTPases participate in cellulase production.

Results

In this study, we found that the putative Ras small GTPase RSR1 negatively regulated the expression of cellulases and xylanases. Deletion of rsr1 (∆rsr1) significantly increased cellulase production and decreased the express

SUBMITTER: Li N 

PROVIDER: S-EPMC10204303 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature