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Synthesis of bis-spiro piperidines using nano γ-alumina supported Sb(v) under ultrasonic irradiation at room temperature conditions.

ABSTRACT: Group VA metalloid ion Lewis acids, Sb(v) was identified as a highly potent catalyst for the one-pot three-component synthesis of bis-spiro piperidine derivatives. The reaction was performed using amines, formaldehyde, and dimedone under ultrasonic irradiation at room temperature. The strong acidic property of the nano γ-alumina supported antimony(v) chloride plays a key role in accelerating the rate of the reaction and initiates the reaction smoothly. The heterogeneous nanocatalyst was fully characterized by FT-IR spectroscopy, XRD, EDS, TGA, FESEM, TEM, and BET techniques. Also, the structures of the prepared compounds were characterized by ¹H NMR and FT-IR spectroscopies.

SUBMITTER: Aghamohammadsadegh M

PROVIDER: S-EPMC10204700 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

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Synthesis of bis-spiro piperidines using nano γ-alumina supported Sb(v) under ultrasonic irradiation at room temperature conditions.

Aghamohammadsadegh Maryam M Bamoniri Abdolhamid A Mirjalili Bi Bi Fatemeh BBF

RSC advances 20230523 23

Group VA metalloid ion Lewis acids, Sb(v) was identified as a highly potent catalyst for the one-pot three-component synthesis of bis-spiro piperidine derivatives. The reaction was performed using amines, formaldehyde, and dimedone under ultrasonic irradiation at room temperature. The strong acidic property of the nano γ-alumina supported antimony(v) chloride plays a key role in accelerating the rate of the reaction and initiates the reaction smoothly. The heterogeneous nanocatalyst was fully ch ...[more]

PMID: 37228678

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