Sinonasal disease among patients with primary ciliary dyskinesia: an international study.

ABSTRACT:

Background

Sinonasal symptoms are a common feature of primary ciliary dyskinesia (PCD); however, literature about their severity and frequency, particularly during the life course, is scarce. Using baseline data from the Ear, nose and throat (ENT) Prospective International Cohort of PCD patients, we describe sinonasal disease in PCD.

Methods

We included participants who had a routine sinonasal examination during which they completed a symptoms questionnaire. We compared frequency of reported symptoms and examination findings among children and adults, and identified characteristics potentially associated with higher risk of sinonasal disease using ordinal regression.

Results

12 centres contributed 384 participants; median age was 16 years (IQR 9-22), and 54% were male

SUBMITTER: Lam YT 

PROVIDER: S-EPMC10204851 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature