COVID-19 pharmaceuticals in aquatic matrices: The threatening effects over cyanobacteria and microalgae.

ABSTRACT: Water contamination by pharmaceuticals is a global concern due to their potential negative effects on aquatic ecosystems and human health. This study examined the presence of three repositioned drugs used for COVID-19 treatment: azithromycin (AZI), ivermectin (IVE) and hydroxychloroquine (HCQ) in water samples collected from three urban rivers in Curitiba, Brazil, during August and September 2020. We conducted a risk assessment and evaluated the individual (0, 2, 4, 20, 100 and 200 μg.L^-1) and combined (mix of the drugs at 2 μg.L^-1) effects of the antimicrobials on the cyanobacterium Synechococcus elongatus and microalga Chlorella vulgaris. The liquid chromatography coupled to mass spectrometry results showed that AZI and IVE were present in all collected samples, whi

SUBMITTER: Marques RZ 

PROVIDER: S-EPMC10205645 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature