Platelet-to-Lymphocyte Ratio and In-Hospital Mortality in Patients With AKI Receiving Continuous Kidney Replacement Therapy: A Retrospective Observational Cohort Study.

ABSTRACT:

Rationale & objective

The platelet-to-lymphocyte ratio (PLR) is a marker of inflammation and a predictor of mortality in a variety of diseases. However, the effectiveness of PLR as a predictor of mortality in patients with severe acute kidney injury (AKI) is uncertain. We evaluated the association between the PLR and mortality in critically ill patients with severe AKI who underwent continuous kidney replacement therapy (CKRT).

Study design

Retrospective cohort study.

Setting & participants

A total of 1,044 patients who underwent CKRT in a single center, from February 2017 to March 2021.

Exposures

PLR.

Outcomes

In-hospital mortality.

Analytical approach

The study patients were classified into quintiles according to the PLR values. A Cox proportion

SUBMITTER: Jeon YH 

PROVIDER: S-EPMC10205757 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature