Association between prehospital end-tidal carbon dioxide levels and mortality in patients with suspected severe traumatic brain injury.

ABSTRACT:

Purpose

Severe traumatic brain injury is a leading cause of mortality and morbidity, and these patients are frequently intubated in the prehospital setting. Cerebral perfusion and intracranial pressure are influenced by the arterial partial pressure of CO₂ and derangements might induce further brain damage. We investigated which lower and upper limits of prehospital end-tidal CO₂ levels are associated with increased mortality in patients with severe traumatic brain injury.

Methods

The BRAIN-PROTECT study is an observational multicenter study. Patients with severe traumatic brain injury, treated by Dutch Helicopter Emergency Medical Services between February 2012 and December 2017, were included. Follow-up continued for 1 year after inclusion. End-tidal

SUBMITTER: Bossers SM 

PROVIDER: S-EPMC10205841 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature