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How the body remembers: Examining the default mode and sensorimotor networks during moral injury autobiographical memory retrieval in PTSD.


ABSTRACT: Neural representations of sensory percepts and motor responses constitute key elements of autobiographical memory. However, these representations may remain as unintegrated sensory and motor fragments in traumatic memory, thus contributing toward re-experiencing and reliving symptoms in trauma-related conditions such as post-traumatic stress disorder (PTSD). Here, we investigated the sensorimotor network (SMN) and posterior default mode network (pDMN) using a group independent component analysis (ICA) by examining their functional connectivity during a script-driven memory retrieval paradigm of (potentially) morally injurious events in individuals with PTSD and healthy controls. Moral injury (MI), where an individual acts or fails to act in a morally aligned manner, is examined given its i

SUBMITTER: Kearney BE 

PROVIDER: S-EPMC10206209 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature