Integrated analysis of robust sex-biased gene signatures in human brain.

ABSTRACT:

Background

Sexual dimorphism is highly prominent in mammals with many physiological and behavioral differences between male and female form of the species. Accordingly, the fundamental social and cultural stratification factors for humans is sex. The sex differences are thought to emerge from a combination of genetic and environmental factors. It distinguishes individuals most prominently on the reproductive traits, but also affects many of the other related traits and manifest in different disease susceptibilities and treatment responses across sexes. Sex differences in brain have raised a lot of controversy due to small and sometimes contradictory sex-specific effects. Many studies have been published to identify sex-biased genes in one or several brain regions, but the assessmen

SUBMITTER: Wapeesittipan P 

PROVIDER: S-EPMC10207743 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature