A pan-cancer analysis identifies SOAT1 as an immunological and prognostic biomarker.
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ABSTRACT:
SUBMITTER: Huang Y
PROVIDER: S-EPMC10207962 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Publications
A pan-cancer analysis identifies SOAT1 as an immunological and prognostic biomarker.
Huang Yangqing Y Zhou Xinlan X Li Xiufen X Huang Dan D Fang Zhong Z Ding Rongrong R
Oncology research 20230410 2
Sterol o-acyltransferase1 (SOAT1) is an enzyme that regulates lipid metabolism. Nevertheless, the predictive value of SOAT1 regarding immune responses in cancer is not fully understood. Herein, we aimed to expound the predictive value and the potential biological functions of SOAT1 in pan-cancer. Raw data related to SOAT1 expression in 33 different types of cancer were acquired from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases. SOAT1 expression was significantly ...[more]
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