Prediabetes and Fracture Risk Among Midlife Women in the Study of Women's Health Across the Nation.

ABSTRACT:

Importance

Whether prediabetes is associated with fracture is uncertain.

Objective

To evaluate whether prediabetes before the menopause transition (MT) is associated with incident fracture during and after the MT.

Design, setting, and participants

This cohort study used data collected between January 6, 1996, and February 28, 2018, in the Study of Women's Health Across the Nation cohort study, an ongoing, US-based, multicenter, longitudinal study of the MT in diverse ambulatory women. The study included 1690 midlife women in premenopause or early perimenopause at study inception (who have since transitioned to postmenopause) who did not have type 2 diabetes before the MT and who did not take bone-beneficial medications before the MT. Start of the MT was defined as the

SUBMITTER: Shieh A 

PROVIDER: S-EPMC10208145 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature