Safety and Tolerability of High-Resolution Esophageal Manometry in Children and Adults.

ABSTRACT:

Introduction

While high-resolution manometry (HRM) is widely accepted as a safe procedure, no study has assessed the safety profile of HRM in clinical practice. This study aimed to determine the safety and tolerability of HRM and to investigate potential determinants of intolerability.

Methods

We obtained HRM procedure reports, demographics, and clinical data (2005-2022) at a tertiary center using electronic chart review. Our primary outcome was HRM tolerability. Multivariable regression was performed to identify associations between the outcome and covariates including age, sex, race, and comorbidities.

Results

A total of 5,107 patients (60.3% female) were included. Of them, 5,050 patients (98.9%) tolerated HRM well and 57 patients (1.1%) did not. Age had a statistic

SUBMITTER: Oh JE 

PROVIDER: S-EPMC10208713 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature