Influence of hyperthermic intraperitoneal chemotherapy on renal blood perfusion.

ABSTRACT:

Purpose

Hyperthermic intraperitoneal chemotherapy (HIPEC) is accompanied with an increased risk of acute kidney injury (AKI). Whether AKI is induced by chemotoxicity or hyperthermia-related changes in renal perfusion remains controversial. The influence of HIPEC on renal perfusion has not been evaluated in patients yet.

Methods

Renal blood perfusion was assessed in ten patients treated with HIPEC by intraoperative renal Doppler pulse-wave ultrasound. Ultrasound (US) examinations were performed pre-, intra-, and postoperative with analyses of time-velocity curves. Patient demographics, surgical details, and data regarding renal function were recorded perioperatively. For evaluation of renal Doppler US to predict AKI, patients were divided in two groups with (AKI +) and withou

SUBMITTER: Liesenfeld LF 

PROVIDER: S-EPMC10209305 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature