Comparison of the oxidative profiles before and after revascularization in peripheral arterial disease: a pilot study.

ABSTRACT: Reactive and highly reactive oxygen species (ROS and hROS) produced by white blood cells are essential for innate immunity; however, they may cause oxidative stress in the host. We developed systems for simultaneously monitoring ROS and hROS, i.e., superoxide radicals (O₂^•-) and hypochlorite ions (OCl^-) secreted from stimulated white blood cells in a few microliters of whole blood. We previously reported on the evaluation of healthy volunteers' blood using the developed system; however, whether patients' blood can be assessed remains unclear. Here, we report a pilot study of 30 cases (28 patients) with peripheral arterial disease, in whom we measured the ROS and hROS levels before and approximately one month after endovascular treatment (EVT) using the syst

SUBMITTER: Takeuchi K 

PROVIDER: S-EPMC10209599 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature