Effects of fructose added to an oral glucose tolerance test on plasma glucose excursions in healthy adults.

ABSTRACT:

Background and objective

Previous experimental studies have shown that fructose interacts with glucose metabolism by increasing hepatic glucose uptake. However, human studies investigating the effects of small ('catalytic') amounts of fructose, added to an oral glucose load, on plasma glucose levels remain inconclusive. The aim of this study, therefore, was to repeat and extend these previous studies by examining the plasma glucose response during a 75 g oral glucose tolerance test (OGTT) with the addition of different doses of fructose.

Methods

Healthy adults (n = 13) received an OGTT without addition of fructose and OGTTs with addition of different doses of fructose (1, 2, 5, 7.5 and 15 g) in a random order, on six separate occasions. Plasma glucose levels were measured ev

SUBMITTER: Buziau AM 

PROVIDER: S-EPMC10209703 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature