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Diversity of the type VI secretion systems in the Neisseria spp.


ABSTRACT: Complete Type VI Secretion Systems were identified in the genome sequence data of Neisseria subflava isolates sourced from throat swabs of human volunteers. The previous report was the first to describe two complete Type VI Secretion Systems in these isolates, both of which were distinct in terms of their gene organization and sequence homology. Since publication of the first report, Type VI Secretion System subtypes have been identified in Neisseria spp. The characteristics of each type in N. subflava are further investigated here and in the context of the other Neisseria spp., including identification of the lineages containing the different types and subtypes. Type VI Secretion Systems use VgrG for delivery of toxin effector proteins; several copies of vgr

SUBMITTER: Calder A 

PROVIDER: S-EPMC10210955 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature