Genomic characterization of enterohaemolysin-encoding haemolytic Escherichia coli of animal and human origin.

ABSTRACT: Enterohaemolysin (Ehx) and alpha-haemolysin are virulence-associated factors (VAFs) causing the haemolytic phenotype in Escherichia coli. It has been shown that chromosomally and plasmid-encoded alpha-haemolysin are characteristic of specific pathotypes, virulence-associated factors and hosts. However, the prevalence of alpha- and enterohaemolysin does not overlap in the majority of pathotypes. Therefore, this study focuses on the characterization of the haemolytic E. coli population associated with multiple pathotypes in human and animal infectious diseases. Using a genomics approach, we investigated characteristic features of the enterohaemolysin-encoding strains to identify factors differentiating enterohaemolysin-positive from alpha-haemolysin-positive E. coli popu

SUBMITTER: Sidorczuk K 

PROVIDER: S-EPMC10210957 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature