Synthesis and characterization of carbohydrate-based biosurfactant mimetics.

ABSTRACT: Glycolipid biosurfactants are of interest for various industry sectors. We report the synthesis and characterization of enantiopure poly-amido-saccharides (PASs) containing myristoyl (C14), palmitoyl (C16), or stearoyl (C18) terminal chain lengths as mimetics of glycolipid biosurfactants. These amphiphilic polymers are water soluble, adopt a helical secondary structure, decompose at temperatures greater than 240 °C, are non-cytotoxic, and self-assemble into nanostructures. Polymers containing the shorter hydrophilic chain lengths and the hydrophobic C14 chain exhibit the lowest surface tension among all polymers.

SUBMITTER: Sockett KA 

PROVIDER: S-EPMC10211081 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature