Dung biomass smoke exposure impairs resolution of inflammatory responses to influenza infection.

ABSTRACT: Epidemiological studies associate biomass smoke with an increased risk for respiratory infections in children and adults in the developing world, with 500,000 premature deaths each year attributed to biomass smoke-related acute respiratory infections including infections caused by respiratory viruses. Animal dung is a biomass fuel of particular concern because it generates more toxic compounds per amount burned than wood, and is a fuel of last resort for the poorest households. Currently, there is little biological evidence on the effects of dung biomass smoke exposure on immune responses to respiratory viral infections. Here, we investigated the impact of dung biomass exposure on respiratory infection using a mouse model of dung biomass smoke and cultured primary human small airway epithe

SUBMITTER: McCarthy CE 

PROVIDER: S-EPMC10211473 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature