Altered resting-state brain activity in functional dyspepsia patients: a coordinate-based meta-analysis.

ABSTRACT:

Background

Neuroimaging studies have identified aberrant activity patterns in multiple brain regions in functional dyspepsia (FD) patients. However, due to the differences in study design, these previous findings are inconsistent, and the underlying neuropathological characteristics of FD remain unclear.

Methods

Eight databases were systematically searched for literature from inception to October 2022 with the keywords "Functional dyspepsia" and "Neuroimaging." Thereafter, the anisotropic effect size signed the differential mapping (AES-SDM) approach that was applied to meta-analyze the aberrant brain activity pattern of FD patients.

Results

A total of 11 articles with 260 FD patients and 202 healthy controls (HCs) were included. The AES-SDM meta-analysis demonstrated

SUBMITTER: Mao Y 

PROVIDER: S-EPMC10213416 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature