Predicting post-exertional malaise in Gulf War Illness based on acute exercise responses.

ABSTRACT:

Aims

Post-exertional malaise (PEM) is poorly understood in Gulf War Illness (GWI). Exercise challenges have emerged as stimuli to study PEM; however, little attention has been paid to unique cardiorespiratory and perceptual responses during exercise. This study tested whether select exercise parameters explained variability in PEM responses.

Main methods

Visual analog scale (0-100) versions of the Kansas questionnaire were used for daily symptom measurements one week before and one week after 30-min of cycling at 70% heart rate reserve in 43 Veterans with GWI and 31 Veteran controls (CON). Cardiopulmonary exercise testing (CPET) methods were used to measure oxygen (VO₂), carbon dioxide (VCO₂), ventilation (VE), heart rate, work rate, and leg muscle pain

SUBMITTER: Boruch AE 

PROVIDER: S-EPMC10214407 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature