A Diverse Array of Large Capsules Transform in Response to Stimuli.

ABSTRACT: The allosteric regulation of biomolecules, such as enzymes, enables them to adapt and alter their conformation to fit specific substrates, expressing different functionalities in response to stimuli. Different stimuli can also trigger synthetic coordination cages to change their shape, size, and nuclearity by reconfiguring the dynamic metal-ligand bonds that hold them together. Here we demonstrate an abiological system consisting of different organic subcomponents and Zn^II metal ions, which can respond to simple stimuli in complex ways. A Zn^II₂₀L₁₂ dodecahedron transforms to give a larger Zn^II₃₀L₁₂ icosidodecahedron through subcomponent exchange, as an aldehyde that forms bidentate ligands is displaced in favor of

SUBMITTER: Wu K 

PROVIDER: S-EPMC10214450 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature