Peanut thresholds in peanut-allergic children are related to dietary composition.

ABSTRACT:

Background

There is no clear explanation for the large variation in threshold levels among peanut-allergic children. We hypothesized that diet composition can partly explain this variation in thresholds, as nutrients and foods influence the intestinal barrier function and microbiota.

Aim

to explore the relationship between the threshold levels for peanut and nutritional intake and gut microbial composition in peanut-allergic children.

Methods

In this explorative cross-sectional study the cumulative threshold levels for peanut were determined by oral food challenge tests. Data on nutrients and foods consumed were obtained from 3-day food diaries. Microbial composition of faeces and saliva were determined by molecular microbiota detection technique. Multivariable linear

SUBMITTER: Luiten D 

PROVIDER: S-EPMC10214579 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature