Incremental predictive value of platelet parameters for preeclampsia: results from a large prospective cohort study.

ABSTRACT:

Background

Platelet parameters during pregnancy were associated with the risk of preeclampsia (PE), but the predictive value of these parameters for PE remained unclear. Our aim was to clarify the individual and incremental predictive value of platelet parameters, including platelet count (PC), mean platelet volume (MPV), plateletcrit (PCT), and platelet distribution width (PDW) for PE.

Methods

This study was based on the Born in Guangzhou Cohort Study in China. Data on platelet parameters were extracted from medical records of routine prenatal examinations. Receiver operating characteristic (ROC) curve was performed to analyze the predictive ability of platelet parameters for PE. Maternal characteristic factors proposed by NICE and ACOG were used to develop the base model.

SUBMITTER: Lin SS 

PROVIDER: S-EPMC10214644 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature