Pharmacopeial quality of artemether-lumefantrine anti-malarial agents in Uganda.

ABSTRACT:

Background

Substandard anti-malarial agents pose a significant challenge to effective malaria control and elimination efforts especially in sub-Saharan Africa. The quality of anti-malarials in most low-and-middle income countries (LMICs) is affected by several factors including inadequate regulation and limited resources. In this study, the pharmacopeial quality of artemether-lumefantrine (AL) in low and high malaria transmission settings in Uganda was assessed.

Methods

This was a cross-sectional study conducted among randomly selected private drug outlets. The AL anti-malarials available in drug outlets were purchased using overt method. The samples were screened for quality using visual inspection, weight uniformity, content assay and dissolution tests. The assay test was

SUBMITTER: Ocan M 

PROVIDER: S-EPMC10214708 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature