N6-methyladenosine RNA modification regulates cotton drought response in a Ca²⁺ and ABA-dependent manner.

ABSTRACT: N⁶ -methyladenosine (m⁶ A) is the most prevalent internal modification present in mRNAs, and is considered to participate in a range of developmental and biological processes. Drought response is highly regulated at the genomic, transcriptional and post-transcriptional levels. However, the biological function and regulatory mechanism of m⁶ A modification in the drought stress response is still poorly understood. We generated a transcriptome-wide m⁶ A map using drought-resistant and drought-sensitive varieties of cotton under different water deficient conditions to uncover patterns of m⁶ A methylation in cotton response to drought stress. The results reveal that m⁶ A represents a common modification and exhibit dramatic chang

SUBMITTER: Li B 

PROVIDER: S-EPMC10214760 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature