Synthesis of 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes via Er(OTf)3-catalyzed cascade reactions of p-quinone methides with 1,3-dicarbonyl compounds† † Electronic supplementary information (ESI) available. CCDC 2246898 and 2248199. For ESI and crystallographic data in CIF or other electronic format see DOI: https://doi.org/10.1039/d3ra02267f

ABSTRACT: The Er(OTf)3-catalyzed cascade cyclization reaction of para-quinone methides (p-QMs) with various 1,3-dicarbonyl compounds has been developed, which efficiently constructed a series of versatile 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes. Herein, we not only propose a novel cyclization strategy of p-QMs, but also provide an easy access to structurally diverse coumarins and chromenes. The Er(OTf)3-catalyzed cascade cyclization reaction of para-quinone methides with various 1,3-dicarbonyl compounds has been developed, which efficiently constructed a series of versatile 4-aryl-3,4-dihydrocoumarins and 4-aryl-4H-chromenes.

SUBMITTER: Bao X 

PROVIDER: S-EPMC10214920 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature