Association of clinical outcomes and connectivity in awake versus asleep deep brain stimulation for Parkinson disease.

ABSTRACT:

Objective

Deep brain stimulation (DBS) for Parkinson disease (PD) is traditionally performed with awake intraoperative testing and/or microelectrode recording. Recently, however, the procedure has been increasingly performed under general anesthesia with image-based verification. The authors sought to compare structural and functional networks engaged by awake and asleep PD-DBS of the subthalamic nucleus (STN) and correlate them with clinical outcomes.

Methods

Levodopa equivalent daily dose (LEDD), pre- and postoperative motor scores on the Movement Disorders Society-Unified Parkinson's Disease Rating Scale part III (MDS-UPDRS III), and total electrical energy delivered (TEED) at 6 months were retroactively assessed in patients with PD who received implants of bilateral DBS

SUBMITTER: Gadot R 

PROVIDER: S-EPMC10215008 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature