Age and Sex Determine Electrocardiogram Parameters in the Octodon degus.

ABSTRACT: Cardiovascular diseases represent the leading cause of mortality and morbidity worldwide, and age is an important risk factor. Preclinical models provide supportive evidence toward age-related cardiac changes, as well as allow for the study of pathological aspects of the disease. In the present work, we evaluated the electrocardiogram (ECG) recording in the O. degus during the aging process in both females and males. Taking into account the age and sex, our study provides the normal ranges for the heart rate, duration and voltage of the ECG waves and intervals, as well as electrical axis deviation. We found that the QRS complex duration and QTc significantly increased with age, whereas the heart rate significantly decreased. On the other hand, the P wave, PR and QTc segments duratio

SUBMITTER: Cuenca-Bermejo L 

PROVIDER: S-EPMC10215068 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature