Effect of Single High Dose Vitamin D Substitution in Hospitalized COVID-19 Patients with Vitamin D Deficiency on Length of Hospital Stay.

ABSTRACT: Vitamin D and its role in the coronavirus-19 disease (COVID-19) pandemic has been controversially discussed, with inconclusive evidence about vitamin D3 (cholecalciferol) supplementation in COVID-19 patients. Vitamin D metabolites play an important role in the initiation of the immune response and can be an easily modifiable risk factor in 25-hydroxyvitamin D₃ (25(OH)D₃)-deficient patients. This is a multicenter, randomized, placebo-controlled double-blind trial to compare the effect of a single high dose of vitamin D₃ followed by treatment as usual (TAU) of daily vitamin D₃ daily until discharge versus placebo plus TAU in hospitalized patients with COVID-19 and 25(OH)D₃-deficiency on length hospital stay. We included 40 patients per g

SUBMITTER: Jaun F 

PROVIDER: S-EPMC10215464 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature