Anaerobic Gram-Negative Bacteria: Role as a Reservoir of Antibiotic Resistance.

ABSTRACT:

Background

Anaerobic Gram-negative bacteria (AGNB) play a significant role as both pathogens and essential members of the human microbiota. Despite their clinical importance, there remains limited understanding regarding their antimicrobial resistance (AMR) patterns. This knowledge gap poses challenges in effectively managing AGNB-associated infections, as empirical treatment approaches may not adequately address the evolving resistance landscape. To bridge this research gap, we conducted a comprehensive study aimed at exploring the role of human AGNB as a reservoir of AMR. This can provide valuable insights for the prevention and management of anaerobic infections.

Methods

We studied the prevalence of AMR and AMR determinants conferring resistance to metronidazole (nimE<

SUBMITTER: Sood A 

PROVIDER: S-EPMC10215933 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature