Catalytic Modification of Porous Two-Dimensional Ni-MOFs on Portable Electrochemical Paper-Based Sensors for Glucose and Hydrogen Peroxide Detection.

ABSTRACT: Rapid and accurate detection of changes in glucose (Glu) and hydrogen peroxide (H₂O₂) concentrations is essential for the predictive diagnosis of diseases. Electrochemical biosensors exhibiting high sensitivity, reliable selectivity, and rapid response provide an advantageous and promising solution. A porous two-dimensional conductive metal-organic framework (cMOF), Ni-HHTP (HHTP = 2,3,6,7,10,11-hexahydroxytriphenylene), was prepared by using a one-pot method. Subsequently, it was employed to construct enzyme-free paper-based electrochemical sensors by applying mass-producing screen-printing and inkjet-printing techniques. These sensors effectively determined Glu and H₂O₂ concentrations, achieving low limits of detection of 1.30 μM and 2.13 μM, a

SUBMITTER: Yang Y 

PROVIDER: S-EPMC10216242 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature