Dermatologic Manifestations of Neurofibromatosis Type 1 and Emerging Treatments

ABSTRACT:

Simple Summary

Neurofibromatosis type 1 (NF1) is a genetic neurophakomatosis (neuroectodermal disorder) associated with a wide array of skin findings. The most recognizable feature is cutaneous neurofibromas; however, less common dermatologic stigmata may also occur. Currently, there are limited therapeutic options for the cutaneous manifestations of NF1. This review summarizes the dermatologic sequelae of NF1 and provides an update on emerging treatments. Appropriate care of these patients often requires interdisciplinary collaboration between neurologists, oncologists, and dermatologists, among other specialties. Increased awareness of these conditions is crucial for providing adequate care to patients with NF1.

Abstract

Neurofibromatosis type 1 (NF1) is an autosomal do

SUBMITTER: Poplausky D 

PROVIDER: S-EPMC10216721 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature