The role of homocysteine levels as a risk factor of ischemic stroke events: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Among numerous risk factors, homocysteine (Hcy) has been linked to cerebral infarction; however, results have been inconsistent. This review aimed to conduct a meta-analysis of published studies to investigate the relationship between plasma Hcy levels and the risk of ischemic stroke.

Methods

A systematic literature search was conducted until November 2022 to obtain articles reporting Hcy levels in ischemic stroke patients. Review Manager software was used to perform all statistical analyses (version 5.3).

Results

Initial investigation yielded 283 articles. The final evaluation included 21 articles, including two prospective studies, one retrospective cohort, and 18 case-control studies. These studies included 9888 participants, of which 5031 were admitte

SUBMITTER: Pinzon RT 

PROVIDER: S-EPMC10216881 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature