Vitamin K supplementation and vascular calcification: a systematic review and meta-analysis of randomized controlled trials

ABSTRACT:

Background

Vascular calcification (VC) is a complex process that has been linked to conditions including cardiovascular diseases and chronic kidney disease. There is an ongoing debate about whether vitamin K (VK) can effectively prevent VC. To assess the efficiency and safety of VK supplementation in the therapies of VC, we performed a systematic review and meta-analysis of recent studies.

Methods

We searched major databases, including PubMed, the Cochrane Library, Embase databases, and Web of Science up until August 2022. 14 randomized controlled trials (RCTs) describing the outcomes of treatment for VK supplementation with VC have been included out of 332 studies. The results were reported in the change of coronary artery calcification (CAC) scores, other artery and val

SUBMITTER:  

PROVIDER: S-EPMC10218696 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature