Direct-Writing Electrospun Functionalized Scaffolds for Periodontal Regeneration: In Vitro Studies.

ABSTRACT: Multiphasic scaffolds that combine different architectural, physical, and biological properties are the best option for the regeneration of complex tissues such as the periodontium. Current developed scaffolds generally lack architectural accuracy and rely on multistep manufacturing, which is difficult to implement for clinical applications. In this context, direct-writing electrospinning (DWE) represents a promising and rapid technique for developing thin 3D scaffolds with controlled architecture. The current study aimed to elaborate a biphasic scaffold using DWE based on two polycaprolactone solutions with interesting properties for bone and cement regeneration. One of the two scaffold parts contained hydroxyapatite nanoparticles (HAP) and the other contained the cementum protein 1 (CEMP

SUBMITTER: Bourdon L 

PROVIDER: S-EPMC10218971 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature