Relationship between the TGFBR1 Gene and Molar Incisor Hypomineralization.

ABSTRACT:

Background

Molar Incisor Hypomineralization Syndrome (MIH) is a problem of increasing incidence that represents a new challenge in the dental treatment of many of the children we see in our dental offices. Understanding the etiology of this syndrome (still unknown) will help us to prevent the appearance of this process. Lately a certain genetic relationship has been suggested in the syndrome. The aim of the present study was to explore the relationship between activation of the TGFBR1 gene and the development of MIH, as recent studies suggest that there may be an association in this regard.

Materials and methods

The study sample consisted of 50 children between 6-17 years of age with MIH, each with at least one parent and a sibling with or without MIH, and a group control of

SUBMITTER: Georgina-Perez L 

PROVIDER: S-EPMC10219479 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature