Optimising Decision Making in Chronic Venous Disease Management with Micronised Purified Flavonoid Fraction.

ABSTRACT: Evidence-based medicine favours randomised controlled trials to limit bias and establish the effects of a treatment with statistical rigour. However, the controlled conditions and careful patient selection of randomised trials may produce results that cannot be generalised to a more diverse patient population in clinical practice. Therefore, there is growing recognition of the importance of supplementing randomised trial data with real-world evidence. Micronised purified flavonoid fraction has been investigated in several large-scale real-world studies, including the RELIEF and DECIDE studies, each of which included more than 1000 patients with chronic venous disease. These studies demonstrated a significant reduction in the prevalence and severity of chronic venous disease symptoms, and a

SUBMITTER: Ulloa JH 

PROVIDER: S-EPMC10220092 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature