Investigating the mechanism of photoisomerization in jellyfish rhodopsin with the counterion at an atypical position.

ABSTRACT: The position of the counterion in animal rhodopsins plays a crucial role in maintaining visible light sensitivity and facilitating the photoisomerization of their retinal chromophore. The counterion displacement is thought to be closely related to the evolution of rhodopsins, with different positions found in invertebrates and vertebrates. Interestingly, box jellyfish rhodopsin (JelRh) acquired the counterion in transmembrane 2 independently. This is a unique feature, as in most animal rhodopsins, the counterion is found in a different location. In this study, we used Fourier Transform Infrared spectroscopy to examine the structural changes that occur in the early photointermediate state of JelRh. We aimed to determine whether the photochemistry of JelRh is similar to that of other animal

SUBMITTER: Inukai S 

PROVIDER: S-EPMC10220492 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature