A User-Centric 3D-Printed Modular Peristaltic Pump for Microfluidic Perfusion Applications.

ABSTRACT: Microfluidic organ-on-a-chip (OoC) technology has enabled studies on dynamic physiological conditions as well as being deployed in drug testing applications. A microfluidic pump is an essential component to perform perfusion cell culture in OoC devices. However, it is challenging to have a single pump that can fulfil both the customization function needed to mimic a myriad of physiological flow rates and profiles found in vivo and multiplexing requirements (i.e., low cost, small footprint) for drug testing operations. The advent of 3D printing technology and open-source programmable electronic controllers presents an opportunity to democratize the fabrication of mini-peristaltic pumps suitable for microfluidic applications at a fraction of the cost of commercial microfluidic pumps. However

SUBMITTER: A Catano J 

PROVIDER: S-EPMC10222968 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature