Ontology highlight
ABSTRACT:
SUBMITTER: Amaya M
PROVIDER: S-EPMC10223282 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Amaya Moushimi M Yin Randy R Yan Lianying L Borisevich Viktoriya V Adhikari Bishwo N BN Bennett Andrew A Malagon Francisco F Cer Regina Z RZ Bishop-Lilly Kimberly A KA Dimitrov Antony S AS Cross Robert W RW Geisbert Thomas W TW Broder Christopher C CC
Viruses 20230428 5
The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in humans and animals, whereas Cedar virus is a nonpathogenic henipavirus. Here, using a recombinant Cedar virus (rCedV) reverse genetics platform, the fusion (F) and attachment (G) glycoprotein genes of rCedV were replaced with those of NiV-Bangladesh (NiV-B) or HeV, generating replication-competent chimeric viruses (rCedV-NiV-B and rCedV-HeV), both with and without green fluorescent protein (GFP) or luciferas ...[more]